Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p207 | (1) | WCRB2014

Effect of extracellular long-chain fatty acids on mouse sperm motility

Moriyama Ryutaro , Wakasa Ikumi , Nakagawa Masako

Free fatty acids are not only energy fuels but also signaling molecules. In fact, long-chain fatty acids (LCFAs) have been identified as the ligands for G protein-coupled receptor 40 and 120 (GPR40 and 120). We have previously observed that GPR120 mRNA is expressed in the mouse sperm head. Based on the result, we hypothesized that the LCFAs act as signaling molecules to regulate sperm motility through GPR120. The aim of present study is to clarify whether extracellular LCFAs a...